Sinus sigmoideus thrombosis secondary to Graves' disease : a case descriptionSinus sigmoideus thrombosis secondary to Graves' disease : a case description
Faculty of Pharmaceutical, Biomedical and Veterinary Sciences . Biomedical Sciences
Neurochemistry and behaviour
Case Reports in Neurology
3(2011):3, p. 203-209
University of Antwerp
Cerebral venous thrombosis (CVT) is a distinct cerebrovascular condition that represents 0.51% of all strokes in the general population. Because of its procoagulant and antifibrinolytic effects [Horne et al.: J Clin Endocrinol Metab 2004;89:44694473], hyperthyroidism has been proposed as a predisposing factor for CVT [Saposnik et al.: Stroke 2011;42:11581192]. For the first time, we describe a 22-year-old right-handed woman with a sinus sigmoideus thrombosis due to Graves disease. Although subclinical hyperthyroidism had been detected 2 years before the onset of neurological symptoms, she did not receive any medical follow-up. Early recognition, diagnosis and treatment are of crucial importance, as Graves disease is a risk factor for CVT and stroke.