Consommation antibiotique hospitalière en France, 1997-2007 : résultats du projet européen ESAC
Faculty of Medicine and Health Sciences
, p. 212-217
University of Antwerp
Objectives. - The knowledge on the level, structure and evolution of the use of antibiotics in the French hospital care is still limited. In addition to the data provided by the European surveillance Antimicrobial consumption (ESAC), the aim of this study is to present the characteristics and general trends of the French hospital antibiotic consumptions. Methods. - Antibiotic used data have been extracted from two different sources. The WHO ATC classification has been used for the analysis. The consumption data have been reported using the French population and the number of bed-days. Results. - During the study period (1997-2007), the antibiotic consumption decreased. Penicillins were the main class of antibiotics used even if their decrease was limited and variation between the types of institutions existed. After an initial increase, the use of cephalosporins decreased after 2001. Use of fluoroquinolones increased in contrast but it was more limited than first expected. Discussion. - A general decrease was observed since 2000, whereas during the same period, antibiotic costs decreased. This decrease could be explained partly by the actions of the national campaigns to reduce antibiotic prescribing in ambulatory care, of new recommendations and of new agreements for prudent use of antibiotics. The increase of awareness of the general antibiotic resistance problem probably went towards modifying behaviours also. (C) 2009 Elsevier Masson SAS. All rights reserved.