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Title
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Pulmonary complaints and lung function after pediatric kidney transplantation
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Author
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Abstract
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| Recently four of 38 children with a kidney transplant were diagnosed with bronchiectasis. The aim of the current study was to identify patients with increased risk for pulmonary damage. In this cross-sectional observational study, children with a functioning kidney graft in the Netherlands and Antwerp, Belgium, were screened with the use of a symptom checklist and spirometry. Maximum score for upper airway complaints was 21 (normal: < 8), for lower airway complaints 28 (< 10). Results of FVC, FEV1 and MEF25 were expressed as percentage predicted for height and sex. One hundred and thirty-five patients completed the interview (122) and/or spirometry (103); 91 did both. Lower airways symptoms were above acceptable levels in 18 (14%) patients. Forty-nine patients (48%) had an abnormal lung function test: in 12 concerning FVC%, in 11 FEV1%, in 24 MEF25% and in 36 FEV1/FVC. Of correlations between symptomatology or spirometry data, and clinical parameters, only that between GFR and MEF25% was statistically significant. Children with a kidney transplant are at increased risk for obstructive lung disease. We recommend to monitor lung function during the follow-up after renal transplantation. |
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Language
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English
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Source (journal)
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Pediatric transplantation. - Copenhagen
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Publication
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Copenhagen
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2008
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ISSN
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1397-3142
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DOI
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10.1111/J.1399-3046.2007.00810.X
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Volume/pages
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12
:2
(2008)
, p. 201-206
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ISI
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000253637400014
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Full text (Publisher's DOI)
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Full text (publisher's version - intranet only)
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