Title
Pulmonary complaints and lung function after pediatric kidney transplantation Pulmonary complaints and lung function after pediatric kidney transplantation
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Publication type
article
Publication
Copenhagen ,
Subject
Human medicine
Source (journal)
Pediatric transplantation. - Copenhagen
Volume/pages
12(2008) :2 , p. 201-206
ISSN
1397-3142
ISI
000253637400014
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
Recently four of 38 children with a kidney transplant were diagnosed with bronchiectasis. The aim of the current study was to identify patients with increased risk for pulmonary damage. In this cross-sectional observational study, children with a functioning kidney graft in the Netherlands and Antwerp, Belgium, were screened with the use of a symptom checklist and spirometry. Maximum score for upper airway complaints was 21 (normal: < 8), for lower airway complaints 28 (< 10). Results of FVC, FEV1 and MEF25 were expressed as percentage predicted for height and sex. One hundred and thirty-five patients completed the interview (122) and/or spirometry (103); 91 did both. Lower airways symptoms were above acceptable levels in 18 (14%) patients. Forty-nine patients (48%) had an abnormal lung function test: in 12 concerning FVC%, in 11 FEV1%, in 24 MEF25% and in 36 FEV1/FVC. Of correlations between symptomatology or spirometry data, and clinical parameters, only that between GFR and MEF25% was statistically significant. Children with a kidney transplant are at increased risk for obstructive lung disease. We recommend to monitor lung function during the follow-up after renal transplantation.
E-info
https://repository.uantwerpen.be/docman/iruaauth/bf9370/8781844.pdf
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