Publication
Title
Trends in age at diagnosis of Turner syndrome
Author
Institution/Organisation
Belgian Study Group for Paediatric Endocrinology
Abstract
The age at diagnosis of 242 girls with Turner syndrome (TS) treated in Belgium with growth hormone between 1991 and 2002 was evaluated. The median (range) age at diagnosis was 6.6 (0-18.3) years Patients with 345,X karyotype were diagnosed earlier than patients with other karyotypes. Compared to a previous survey, performed on 100 patients 12 years earlier, more patients were diagnosed during infancy and childhood, and less during adolescence. However, in 22% of the girls the diagnosis was made after the age of 12 years; these girls showed the largest height deficit. As early diagnosis has several potential advantages we recommend that a cytogenetic analysis should be considered in all girls with unexplained short stature with height below -2 SD of the mean for age or below the parent specific lower limit of height.
Language
English
Source (journal)
Archives of disease in childhood. - London, 1926, currens
Publication
London : 2005
ISSN
0003-9888 [print]
1468-2044 [online]
Volume/pages
90:3(2005), p. 267-268
ISI
000227435800015
Full text (Publisher's DOI)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 24.02.2012
Last edited 15.07.2017
To cite this reference