Hymenoptera venom allergy
Faculty of Medicine and Health Sciences
Bologna :Medimond, 2003
Allergy Week 2003, November 15-19, 2003, Ghent, Belgium
University of Antwerp
For most people, Hymenoptera stings produce only a transient and bothersome local inflammatory reaction charactcrised b pain, redness and swelling. However, for those who are allergic to components of the venom, a re-sting may cause life-threatening, even fatal, reactions. In such patients correct diagnosis is a prerequisite for effective management, i.e. specific venom immunotherapy (VIT) and generally consists of appropriate skin testing and quantification of venom-specific IgE-antibodies. In spite the high efficiency of properly administered VIT, the molecular and cellular mechanisms of the desensitisation process remain incompletely understood.