Publication
Title
Mass spectrometric identification of phosphorylated vasostatin II, a chromogranin A-derived protein fragment (1-113)
Author
Abstract
Vasostatin II, an N-terminal chromogranin A-derived protein (CGA(1-113)), was purified from bovine chromaffin granule lysate and characterized by electrospray mass spectrometry (ES/MS) as being partially phosphorylated. The phosphorylation site was determined to be at the Ser(81) position by mass spectrometric peptide mapping and tandem mass spectrometric analysis. This phosphorylation site is close to the processing site (...QKK(78)HSS(p)(81)...) yielding vasostatin I, an N-terminal CGA-derived peptide comprising residues 1-76, suggesting that phosphorylation at Ser(81) is involved in the formation of vasostatin I in chromaffin cells. (C) 1997 Elsevier Science B.V.
Language
English
Source (journal)
Biochimica et biophysica acta : P : protein structure and molecular enzymology. - Amsterdam, 1982 - 2002
Publication
Amsterdam : 1997
ISSN
0167-4838
Volume/pages
1343:2(1997), p. 287-298
ISI
000071237500016
Full text (Publishers DOI)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 01.03.2012
Last edited 09.05.2017
To cite this reference