Title
Exit from proliferation during leaf development in **Arabidopsis thaliana** : a not-so-gradual process Exit from proliferation during leaf development in **Arabidopsis thaliana** : a not-so-gradual process
Author
Faculty/Department
Faculty of Sciences. Biology
Publication type
article
Publication
Cambridge, Mass. ,
Subject
Biology
Human medicine
Source (journal)
Developmental cell. - Cambridge, Mass.
Volume/pages
22(2012) :1 , p. 64-78
ISSN
1534-5807
ISI
000299365800010
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
Early leaf growth is sustained by cell proliferation and subsequent cell expansion that initiates at the leaf tip and proceeds in a basipetal direction. Using detailed kinematic and gene expression studies to map these stages during early development of the third leaf of Arabidopsis thaliana, we showed that the cell-cycle arrest front did not progress gradually down the leaf, but rather was established and abolished abruptly. Interestingly, leaf greening and stomatal patterning followed a similar basipetal pattern, but proliferative pavement cell and formative meristemoid divisions were uncoordinated in respect to onset and persistence. Genes differentially expressed during the transition from cell proliferation to expansion were enriched in genes involved in cell cycle, photosynthesis, and chloroplast retrograde signaling. Proliferating primordia treated with norflurazon, a chemical inhibitor of retrograde signaling, showed inhibited onset of cell expansion. Hence, differentiation of the photosynthetic machinery is important for regulating the exit from proliferation.
Full text (open access)
https://repository.uantwerpen.be/docman/irua/545d98/5020.pdf
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