Title
Can cytogenetics explain the possible association between exposure to extreme low-frequency magnetic fields and Alzheimer's disease? Can cytogenetics explain the possible association between exposure to extreme low-frequency magnetic fields and Alzheimer's disease?
Author
Faculty/Department
Faculty of Pharmaceutical, Biomedical and Veterinary Sciences . Biomedical Sciences
Publication type
article
Publication
Chichester ,
Subject
Pharmacology. Therapy
Source (journal)
Journal of applied toxicology. - Chichester
Volume/pages
32(2012) :2 , p. 81-87
ISSN
0260-437X
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Abstract
Recently, a number of epidemiological studies have suggested that occupational as well as residential exposure to extreme low-frequency electromagnetic fields (ELF-EMFs) may be a risk factor for Alzheimer's disease. This is not proven yet and there are no known biological mechanisms to explain this alleged association. Alzheimer's disease is characterized by a number of events that have, at least partially, a genetic origin. In particular, trisomy of chromosomes 17 and 21 seems to be involved. Overall ELF-EMFs have not been identified as genotoxic agents, but there are some papers in the scientific literature that indicate that they may enhance the effects of agents that are known to induce mutations or tumors. There are also some indications that ELF-EMFs may induce aneuploïdy. This opens some perspectives for investigating the alleged association between ELF-EMFs and Alzheimer's. This paper reviews the possibility of a cytogenetic association between the electromagnetic fields and Alzheimer's disease.
E-info
https://repository.uantwerpen.be/docman/iruaauth/ece09c/d11269b5719.pdf