|
Title
|
|
|
|
First evidence of high knockdown resistance frequency in **Anopheles arabiensis** (Diptera: Culicidae) from Ethiopia
|
|
|
Author
|
|
|
|
|
|
|
Abstract
|
|
|
|
| The status of knockdown resistance (kdr) mutation was investigated in the major malaria vector Anopheles arabiensis Patton (Diptera: Culicidae) from Ethiopia. Among 240 mosquito samples from 15 villages of southwestern Ethiopia that were screened by allele-specific polymerase chain reaction for kdr mutations, the West African kdr mutation (L1014F) was detected in almost all specimens (98.5%), whereas the East African kdr mutation (L1014S) was absent. Moreover, the mortality of An. gambiae s.l. to diagnostic dosages of 4% DDT, 0.75% permethrin, and 0.05% deltamethrin from bioassay results was 1.0%, 18.1%, and 82.2%, respectively. We report here the highest kdr allele frequency ever observed in An. arabiensis and its implications in malaria vector control in Ethiopia are discussed. |
|
|
|
Language
|
|
|
|
English
|
|
|
Source (journal)
|
|
|
|
The American journal of tropical medicine and hygiene. - Baltimore, Md
|
|
|
Publication
|
|
|
|
Baltimore, Md
:
2010
|
|
|
ISSN
|
|
|
|
0002-9637
|
|
|
DOI
|
|
|
|
10.4269/AJTMH.2010.09-0738
|
|
|
Volume/pages
|
|
|
|
83
:1
(2010)
, p. 122-125
|
|
|
ISI
|
|
|
|
000279366300025
|
|
|
Full text (Publisher's DOI)
|
|
|
|
|
|
|
Full text (publisher's version - intranet only)
|
|
|
|
|
|