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Title
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First evidence of high knockdown resistance frequency in **Anopheles arabiensis** (Diptera: Culicidae) from Ethiopia
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Author
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Abstract
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| The status of knockdown resistance (kdr) mutation was investigated in the major malaria vector Anopheles arabiensis Patton (Diptera: Culicidae) from Ethiopia. Among 240 mosquito samples from 15 villages of southwestern Ethiopia that were screened by allele-specific polymerase chain reaction for kdr mutations, the West African kdr mutation (L1014F) was detected in almost all specimens (98.5%), whereas the East African kdr mutation (L1014S) was absent. Moreover, the mortality of An. gambiae s.l. to diagnostic dosages of 4% DDT, 0.75% permethrin, and 0.05% deltamethrin from bioassay results was 1.0%, 18.1%, and 82.2%, respectively. We report here the highest kdr allele frequency ever observed in An. arabiensis and its implications in malaria vector control in Ethiopia are discussed. |
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Language
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English
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Source (journal)
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The American journal of tropical medicine and hygiene. - Baltimore, Md
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Publication
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Baltimore, Md
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2010
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ISSN
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0002-9637
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Volume/pages
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83
:1
(2010)
, p. 122-125
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ISI
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000279366300025
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Full text (Publisher's DOI)
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Full text (publisher's version - intranet only)
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