Title
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Transition metal-catalyzed N-arylations of amidines and guanidines
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Author
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Abstract
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Although several recent reviews dealt with transition metal catalyzed N-arylation of amines (all classes), to date no specific review covering the N-arylation of amidines and guanidines appeared. Amidines and guanidines are considered as fundamental entities in medicinal chemistry. The appearance of these functional groups in drugs, agrochemicals and natural products justifies a separate description of the current status of the literature on the N-arylation of the amidine and guanidine functionalities. Both acyclic and cyclic derivatives are taken into account. For cyclic amidines/guanidines only systems which possess an exocyclic nitrogen atom are considered. This critical review is largely organized by the type of amidine/guanidine and transition metal used and covers literature up to May 2011 (200 references). |
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Language
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English
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Source (journal)
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Chemical Society reviews. - London
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Publication
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London
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2012
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ISSN
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0306-0012
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DOI
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10.1039/C1CS15236J
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Volume/pages
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41
:6
(2012)
, p. 2463-2497
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ISI
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000300797700024
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Full text (Publisher's DOI)
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