Title
Nebulization treatment with saline compared to bromhexine in treating chronic sinusitis in asthmatic children Nebulization treatment with saline compared to bromhexine in treating chronic sinusitis in asthmatic children
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Publication type
article
Publication
Copenhagen ,
Subject
Human medicine
Source (journal)
Allergy: European journal of allergy and clinical immunology. - Copenhagen
Volume/pages
42(1987) :1 , p. 33-36
ISSN
0105-4538
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
Twenty children aged 3 to 14 years with a history of bronchial asthma complicated by chronic sinusitis were studied in a double-blind study. Patients received, at random, over a period of 2 weeks, either 2 ml saline or 2 ml bromhexine (2 mg/ml) t.i.d. by means of a home nebulizer. A significant decline of clinical symptoms during both nebulization treatments as compared to the pretreatment symptom score was observed (mean score of 1.5 ± 0.7 and 0.5 ± 0.8, respectively, (P 0.01). Both types of nebulization were equally efficient in reducing the symptom score. Radiological abnormalities were significantly more reversed after saline nebulization as compared with bromhexine (P< 0.05), although both treatments showed radiological improvement (P< 0.01). The present study indicates that nebulization with saline may have some beneficial effect on chronic sinusitis in asthmatic children. Bromhexine was not superior to saline for this purpose.
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