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Title
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Nebulization treatment with saline compared to bromhexine in treating chronic sinusitis in asthmatic children
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Author
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Abstract
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| Twenty children aged 3 to 14 years with a history of bronchial asthma complicated by chronic sinusitis were studied in a double-blind study. Patients received, at random, over a period of 2 weeks, either 2 ml saline or 2 ml bromhexine (2 mg/ml) t.i.d. by means of a home nebulizer. A significant decline of clinical symptoms during both nebulization treatments as compared to the pretreatment symptom score was observed (mean score of 1.5 ± 0.7 and 0.5 ± 0.8, respectively, (P 0.01). Both types of nebulization were equally efficient in reducing the symptom score. Radiological abnormalities were significantly more reversed after saline nebulization as compared with bromhexine (P< 0.05), although both treatments showed radiological improvement (P< 0.01). The present study indicates that nebulization with saline may have some beneficial effect on chronic sinusitis in asthmatic children. Bromhexine was not superior to saline for this purpose. |
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Language
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English
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Source (journal)
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Allergy: European journal of allergy and clinical immunology. - Copenhagen
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Publication
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Copenhagen
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1987
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ISSN
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0105-4538
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DOI
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10.1111/J.1398-9995.1987.TB02184.X
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Volume/pages
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42
:1
(1987)
, p. 33-36
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Full text (Publisher's DOI)
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