Slow decline of tumour markers in a patient with testicular cancer and cystic metastases : does it always reflect chemoresistance?Slow decline of tumour markers in a patient with testicular cancer and cystic metastases : does it always reflect chemoresistance?
Faculty of Medicine and Health Sciences
Antwerp Surgical Training, Anatomy and Research Centre (ASTARC)
Molecular Imaging, Pathology, Radiotherapy & Oncology (MIPRO)
Belgian journal of medical oncology. - Amsterdam, 2007, currens
5(2011):5, p. 199-204
University of Antwerp
Testicular cancer is of particular interest as metastatic disease can be cured. Sometimesdiagnosis can be difficult when the patient presents other signs and symptoms than a testicular mass. The importance of a thorough clinical examination is emphasised by the present case. During therapy, a satisfactory decrease of the tumour markers is an important significant positive prognostic factor. A case is presented with a remarkably slow decrease of the tumour markers, possibly due to leakage from cystic metastases. In such patients, the evolution of the tumour markers is probably not indicative for the prognosis, and possibly not reflecting a pattern of chemoresistance.