Publication
Title
Antimicrobial activity of some **Clerodendrum** species from Egypt
Author
Abstract
Chloroformic and methanolic extracts of four Clerodendrum species cultivated in Egypt were screened for antimicrobial activities. Chloroformic extracts of the flowers of Clerodendrum chinense and Clerodendrum splendens were active against Plasmodium falciparum (IC50 < 10 µg mL−1). Chloroformic extracts of the stem and flowers of C. chinense were active against Trypanosoma cruzi (IC50 = 1.21 and 1.12 µg mL−1, respectively) with marginal cytotoxicity. Chloroformic extracts of the leaves of C. chinense and C. splendens showed promising activities against T. cruzi (IC50 = 3.39 and 1.98 µg mL−1, respectively) without cytotoxic effect on a human cell line. None of the selected plants showed significant activity against Gram-negative or Gram-positive bacteria or Candida albicans. Verbascoside, a phenyl propanoid glycoside isolated from the leaves of C. chinense, showed marginal activity against T. cruzi. Rengyolone, a cyclohexyl ethanoid isolated from the leaves of C. chinense, showed a broad but not specific activity against the tested organisms.
Language
English
Source (journal)
Natural product research / UNESCO. - Paris
Publication
Paris : 2013
ISSN
1478-6419
Volume/pages
27:11(2013), p. 1032-1036
ISI
000320641900015
Full text (Publishers DOI)
Full text (publishers version - intranet only)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 31.05.2012
Last edited 21.04.2017
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