Title
Imaging studies in the diagnostic workup of neonatal nasal obstruction
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Publication type
article
Publication
New York, N.Y. ,
Subject
Human medicine
Source (journal)
Journal of computer assisted tomography. - New York, N.Y., 1977, currens
Volume/pages
25(2001) :4 , p. 540-549
ISSN
0363-8715
1532-3145
ISI
000169784700006
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Abstract
Twelve neonates presenting with nasal obstruction after birth were evaluated by imaging studies for diagnostic reasons. Four groups were recognized: Group I: choanal atresia (n 5) and choanal stenosis (n 1); Group II: congenital nasal pyriform aperture stenosis (CNPAS) (n 3) and holoprosencephaly (n 1); Group III: nasolacrimal duct mucocele (n 1); Group IV: nasal hypoplasia (n 1). Associated anomalies were found in eight patients. Four patients with choanal atresia showed manifestations of the CHARGE (coloboma, congenital heart defect, atretic choanae, retarded physical and neuromotor development associated with central nervous system anomalies, genital hypoplasia, and ear anomaly and/or deafness) association. In the fifth patient with choanal atresia, the diagnosis of amnion disruption sequence was made. One patient with CNPAS had a solitary maxillary central incisor (SMCI), a mild form of holoprosencephaly. Besides proboscis and synophthalmos, SMCI was also present in the holoprosencephaly case. The patient with severe nasal hypoplasia had warfarin embryopathy. This review emphasizes the need for performing imaging studies in the diagnostic workup of neonates born with nasal obstruction.
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