Publication
Title
Histamine nasal provocation test : an evaluation of active anterior rhinomanometry and of threshold criteria of provocative dose
Author
Abstract
This study is a methodological approach to histamine nasal provocation. The test uses active anterior rhinomanometry and a histamine titration method, challenging both nasal cavities with a metered dose pump. It has been confirmed that the histamine nasal provocation test can differentiate between controls and non-allergic rhinitis patients. This study shows, moreover, that the method is more sensitive in assessing response to histamine provocation when a 25% increase of post-saline nasal airway resistance (PD25) is considered than a PD50 or PD100 criterion. The histamine response, was found to be independent of the baseline nasal airway resistance value. Pronounced unilateral responsiveness was frequently noticed. Both nasal cavities should be challenged and the most reactive side considered.
Language
English
Source (journal)
Allergy: European journal of allergy and clinical immunology. - Copenhagen
Publication
Copenhagen : 1989
ISSN
0105-4538
DOI
10.1111/J.1398-9995.1989.TB04187.X
Volume/pages
44 :7 (1989) , p. 482-486
Full text (Publisher's DOI)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Record
Identifier
Creation 07.06.2012
Last edited 04.03.2024
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