Title
Grammar disruption in a patient with Neuro-Sweet syndrome Grammar disruption in a patient with Neuro-Sweet syndrome
Author
Faculty/Department
Faculty of Arts. Linguistics and Literature
Faculty of Pharmaceutical, Biomedical and Veterinary Sciences . Biomedical Sciences
Publication type
article
Publication
Oxford ,
Subject
Human medicine
Linguistics
Source (journal)
Neurocase. - Oxford, 1997, currens
Volume/pages
18(2012) :3 , p. 235-247
ISSN
1355-4794
ISI
000303565400007
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Abstract
This paper for the first time reports detailed neurolinguistic findings in a patient with Neuro-Sweet syndrome. In this patient the presenting symptoms of central nervous system (CNS) involvement primarily consisted of a selective grammar deficit restricted to spontaneous speech. On MRI a left prefrontal ischemic stroke (superior part BA 6) and two small subcortical left parietal infarctions were found. Neurolinguistic analyses, however, did not reveal a profile consistent with any observations of agrammatism caused by structural damage to the language areas critically involved in grammatical processing. It is hypothesized that selectively distorted grammar might reflect disruption of the frontosubcortical network involved in language processing. Prefrontal neurobehavioral abnormalities associated with functional disruption of the inferior medial frontal regions as demonstrated by SPECT, additionally suggest that agrammatic symptoms may be linked to a higher-level cognitive disorder following encephalopathic CNS involvement.
E-info
https://repository.uantwerpen.be/docman/iruaauth/00ed50/0494dfea3c1.pdf
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Handle