Can liquid supercooling and glassy-like structure be invoked to interpret collective cell behaviour in the human body?
Faculty of Sciences. Physics
Physics and chemistry of liquids. - London
, p. 137-151
University of Antwerp
The present authors have lately been concerned with two distinct areas which are brought together in this topical review. The first deals with aqueous droplet encapsulation of a single cell, either normal or cancerous, in which the cell volume is quite comparable with that of the droplet. We already pointed out there the future possibilities for assessing how such a single cell might be substantially modified when it is a member of an ensemble of cells in the human body and such cellular heterogeneity is reviewed here. The second area, studied by one of us in conjunction with Alonso, concerns the structure factor S(q) in a supercooled liquid in comparison with that below the glass transition temperature. This article assesses how liquid supercooling and glassy behaviour may also be useful concepts for furthering our understanding of collective cell behaviour in the human body.