Publication
Title
Structures of alkyl-substituted Troger's base derivatives illustrate the importance of Z ' for packing in the absence of strong crystal synthons
Author
Abstract
Crystal structures of Troger's base (5,11-methano-2,8-dimethyl-5,6,11,12-tetrahydrodibenzo[b, f][1,5] diazocine) analogues with the methyl groups replaced by ethyl, iso-propyl and tert-butyl groups were studied. The incidence of Z' > 1 structures increases to rather conspicuous levels. The reasons behind this trend are expanded upon, and a possible explanation is given in the flexibility of the alkyl substituents and van der Waals stabilization. In combination these effects allow for an additional stabilization of the packing by small changes in the molecular conformations, thus expanding the size of the asymmetric unit.
Language
English
Source (journal)
Acta crystallographica: section B: structural science. - Copenhagen
Publication
Copenhagen : 2010
ISSN
0108-7681
Volume/pages
66:4(2010), p. 472-481
ISI
000279806100008
Full text (Publishers DOI)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 12.07.2012
Last edited 26.03.2017
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