Title
Detection of mycobacterium-leprae by the polymerase chain-reaction in nasal swabs of leprosy patients and their contacts Detection of mycobacterium-leprae by the polymerase chain-reaction in nasal swabs of leprosy patients and their contacts
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Publication type
article
Publication
Manila ,
Subject
Biology
Human medicine
Source (journal)
International journal of leprosy and other mycobacterial diseases / International Leprosy Association. - Manila
Volume/pages
61(1993) :3 , p. 389-393
ISSN
0148-916X
ISI
A1993MJ37800002
Carrier
E
Target language
English (eng)
Affiliation
University of Antwerp
Abstract
Nose swabs from 4 paucibacillary (PB) and 8 multibacillary (MB) leprosy patients and their contacts were tested for the presence of Mycobacterium leprae by two polymerase chain reactions (PCR); 30% of the samples contained inhibitors for the PCR, 1 of 52 (1.9%) swabs and 13 of 164 (7.9%) swabs were positive for M. leprae among contacts of PB and MB patients, respectively. Since this difference is not significant, and some positives were found among contacts of MB patients treated and cured of their infection, it is concluded that the observed infections are community acquired.
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